Neurocardiology describes the interactions between the nervous and cardiovascular systems. Stress-related cardiomyopathy is an example of a brain-heart connection that occurs in several acute brain injury conditions that share sympathetic activation. Brain effects on the heart may include elevated cardiac markers, arrhythmias, ECG repolarization abnormalities, myocardial necrosis, and autonomic dysfunction. Neurogenic fainting myocardium in aneurysmal subarachnoid haemorrhage represents one end of the spectrum and is associated with explosive increases in intracranial pressure, leading to excess catecholamines and possibly CBN. The brain-heart connection is better known to cardiologists than to neurologists. This chapter provides some insight into the pathophysiology of these pathological neuro-cardiac disorders and the most appropriate treatments for neurologists.